Channelized hotelling and human observer correlation for lesion detection in hepatic SPECT imaging.

Mathematic "model" observers that predict human performance are of interest in medical imaging as substitutes in psychophysical studies. We have examined the correlations between human observers and several forms of the channelized Hotelling observer (CHO) for a tumor detection task with simulated SPECT liver images that were used to study the effects of scatter and scatter correction on detection.A receiver operating characteristic (ROC) study...