Endoscopic Ultrasound-Guided Fine Needle Aspiration versus Percutaneous Ultrasound-Guided Fine Needle Aspiration in Diagnosis of Focal Pancreatic Masses.

Published on Oct 1, 2013in Endoscopic ultrasound5.628
· DOI :10.4103/2303-9027.121239
Hussein Hassan Okasha10
Estimated H-index: 10
(Cairo University),
Mazen Naga6
Estimated H-index: 6
(Cairo University)
+ 8 AuthorsAyman Foda2
Estimated H-index: 2
(Cairo University)
Sources
Abstract
Objective: Pancreatic carcinoma is one of the leading cancer morbidity and mortality world-wide. Controversy has arisen about whether the percutaneous approach with computed tomography/ultrasonography-guidance fine needle aspiration (US-FNA) or endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is the preferred method to obtain diagnostic tissue. Our purpose of this study is to compare between the diagnostic accuracy of EUS-FNA and percutaneous US-FNA in diagnosis of pancreatic cancer. Patients and Methods: A total of 197 patients with pancreatic masses were included in the study, 125 patients underwent US-FNA (Group 1) and 72 patients underwent EUS-FNA (Group 2). Results: EUS-FNA has nearly the same accuracy (88.9%) as US-FNA (87.2%) in diagnosis of pancreatic cancer. The sensitivity, specificity, positive predictive value and negative predictive value for EUS-FNA was 84%, 100%, 100%, 73.3% respectively. It was 85.5%, 90.4%, 94.7%, 76% respectively for US-FNA. EUS-FNA had a lower complication rate (1.38%) than US-FNA (5.6%). Conclusion: EUS-FNA has nearly the same accuracy as US-FNA of pancreatic masses with a lower complication rate.
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#1Michael Jonathan Hewitt (West Middlesex University Hospital)H-Index: 2
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Background Preoperative diagnosis of solid pancreatic lesions remains challenging despite advancement in imaging technologies. EUS has the benefit of being a minimally invasive, well-tolerated procedure, although results are operator-dependent. The addition of FNA (EUS-guided FNA) provides samples for cytopathologic analysis, a major advantage over other imaging techniques. Objective To determine the diagnostic accuracy of EUS-FNA for pancreatic cancer. Design This is a meta-analysis of publishe...
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This article is part of a combined publication that expresses the current view of the European Society of Gastrointestinal Endoscopy (ESGE) about endoscopic ultrasound (EUS)-guided sampling in gastroenterology, including EUS-guided fine needle aspiration (EUS-FNA) and EUS-guided trucut biopsy (EUS-TCB), of submucosal tumors, diffuse esophageal/gastric wall thickening, pancreatic solid masses and cystic-appearing lesions, mediastinal lesions unrelated to lung or esophageal cancer, cancer of the e...
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Background Diagnosing pancreatic cancer by EUS-FNA is a potentially appealing alternative to percutaneous biopsy. Aim To compare EUS-FNA with CT or US-guided FNA for diagnosing pancreatic cancer. Design Single center, prospective, randomized, cross-over. Setting Duke University Medical Center. Population Eighty-four patients referred with suspicious solid pancreatic mass lesions randomized to CT/US-FNA (n = 43) or EUS-FNA (n = 41). Intervention Patients underwent an imaging procedure/FNA. If cyt...
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P C Bornman is professor of surgery, University of Cape Town, South Africa. The ABC of diseases of liver, pancreas, and biliary system is edited by I J Beckingham, consultant hepatobiliary and laparoscopic surgeon, department of surgery, Queen's Medical Centre, Nottingham (ku.ca.mahgnitton@mahgnikceB.naI). The series will be published as a book later this year.
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