Gleaning multicomponent T₁ and T₂ information from steady‐state imaging data

The driven‐equilibrium single‐pulse observation of T 1 (DESPOT1) and T 2 (DESPOT2) are rapid, accurate, and precise methods for voxelwise determination of the longitudinal and transverse relaxation times. A limitation of the methods, however, is the inherent assumption of single‐component relaxation. In a variety of biological tissues, in particular human white matter (WM) and gray matter (GM), the relaxation has been shown to be more completely...