Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI
Abstract
Pyruvate is included in the energy production of the heart muscle and is metabolized into lactate, alanine, and CO 2 in equilibrium with HCO . The aim of this study was to evaluate the feasibility of using 13 C hyperpolarization enhanced MRI to monitor pyruvate metabolism in the heart during an ischemic episode. The left circumflex artery of pigs (4 months, male, 29–34 kg) was occluded for 15 or 45 min followed by 2 hr of reperfusion. Pigs were...
Paper Details
Title
Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI
Published Date
Apr 21, 2008
Volume
59
Issue
5
Pages
1005 - 1013
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