Natural history study

Amyotrophic lateral sclerosis

Biopsy

Weakness

Natural history

Muscular dystrophy

Pediatrics

Anatomy

Progressive muscular atrophy

Age of onset

Myopathy

Atrophy

Internal medicine

Medicine

Physical medicine and rehabilitation

Disease

Muscle biopsy

Pathology

Brain

Miyoshi-type distal muscular dystrophy has now been found to be more frequent outside Japan than was previously thought.We studied 24 Dutch patients with Miyoshi-type distal muscular dystrophy and focused on its clinical expression and natural history, muscle CT-scans and muscle biopsy findings.Our study shows that Miyoshi myopathy is a heterogeneous, slowly progressive disorder.The disease starts with weakness and atrophy of the calves and

Miyoshi-type distal muscular dystrophy. Clinical spectrum in 24 Dutch patients