Tension is required but not sufficient for focal adhesion maturation without a stress fiber template
Abstract
Focal adhesion composition and size are modulated in a myosin II-dependent maturation process that controls adhesion, migration, and matrix remodeling. As myosin II activity drives stress fiber assembly and enhanced tension at adhesions simultaneously, the extent to which adhesion maturation is driven by tension or altered actin architecture is unknown. We show that perturbations to formin and α-actinin 1 activity selectively inhibited stress...
Paper Details
Title
Tension is required but not sufficient for focal adhesion maturation without a stress fiber template
Published Date
Jan 30, 2012
Journal
Volume
196
Issue
3
Pages
363 - 374
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History