CT Perfusion Mean Transit Time Maps Optimally Distinguish Benign Oligemia from True “At-Risk” Ischemic Penumbra, but Thresholds Vary by Postprocessing Technique

BACKGROUND AND PURPOSE:

Various CTP parameters have been used to identify ischemic penumbra. The purpose of this study was to determine the optimal CTP parameter and threshold to distinguish true “at-risk” penumbra from benign oligemia in acute stroke patients without reperfusion.

MATERIALS AND METHODS:

Consecutive stroke patients were screened and 23 met the following criteria: 1) admission scanning within 9 hours of onset, 2)...