A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol
Abstract
This study examines the current knowledge of physiological and clinical effects of tetrahydrocannabinol (THC) and cannabidiol (CBD) and presents a rationale for their combination in pharmaceutical preparations. Cannabinoid and vanilloid receptor effects as well as non-receptor mechanisms are explored, such as the capability of THC and CBD to act as anti-inflammatory substances independent of cyclo-oxygenase (COX) inhibition. CBD is demonstrated...
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Paper Details
Title
A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol
DOI
Published Date
Jan 1, 2006
Journal
Volume
66
Issue
2
Pages
234 - 246
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