Review paper
At the Bench:Helicobacter pylori, dysregulated host responses, DNA damage, and gastric cancer
Abstract
Helicobacter pylori infection is the strongest known risk factor for the development of gastric cancer. Given that ∼50% of the global population is infected with this pathogen, there is great impetus to elucidate underlying causes that mediate progression from infection to cancer. Recent evidence suggests that H. pylori-induced chronic inflammation and oxidative stress create an environment conducive to DNA damage and tissue injury. DNA damage...
Paper Details
Title
At the Bench:Helicobacter pylori, dysregulated host responses, DNA damage, and gastric cancer
Published Date
May 27, 2014
Journal
Volume
96
Issue
2
Pages
201 - 212
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Notes
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