An isotope-dilution, GC–MS assay for formate and its application to human and animal metabolism
Abstract
Formate, a crucial component of one-carbon metabolism, is increasingly recognized as an important intermediate in production and transport of one-carbon units. Unlike tetrahydrofolate-linked intermediates, it is not restricted to the intracellular milieu so that circulating levels of formate can provide insight into cellular events. We report a novel isotope-dilution, GC–MS assay employing derivatization by 2,3,4,5,6-pentafluorobenzyl bromide...
Paper Details
Title
An isotope-dilution, GC–MS assay for formate and its application to human and animal metabolism
Published Date
Apr 10, 2014
Journal
Volume
46
Issue
8
Pages
1885 - 1891
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History