A study of the inhibition of tumor growth in mice and rats with 10‐methyl‐1,2‐benzan‐thracene and derivatives related to the nitrogen and sulfur beta‐chloroethyl vesicants

Published on Jul 1, 1949in Cancer5.742

· DOI :10.1002/1097-0142(194907)2:4<701::AID-CNCR2820020417>3.0.CO;2-K

Arnold M. Seligman12

Estimated H-index: 12

(BIDMC: Beth Israel Deaconess Medical Center), Myron Milden1

Estimated H-index: 1

(BIDMC: Beth Israel Deaconess Medical Center), Orrie M. Friedman1

Estimated H-index: 1

(BIDMC: Beth Israel Deaconess Medical Center)

Abstract

References (23)

References23

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Distribution studies in mice following intravenous injection of methyl‐bis (β‐iodoethyl) amine hydrochloride prepared with radioactive iodine

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#1Arnold M. Seligman (Harvard University)H-Index: 18

#2Orrie M. Friedman (Harvard University)H-Index: 13

Last. Alexander M. Rutenburg (Harvard University)H-Index: 14

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5 Citations Source

Distribution studies in mice following the intravenous injection of diethyl beta-iodoethyl amine hydrochloride prepared with radioactive iodine.

Feb 1, 1949·Journal of the National Cancer Institute11.58

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Derivatives of 10-Methyl-1,2-benzanthracene Related to the Nitrogen and Sulfur beta-Chloroethyl Vesicants1a

Sep 1, 1948·Journal of the American Chemical Society14.61

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The relation between growth inhibition, toxicity and protein metabolism in rats treated with 1:2:5:6-dibenzanthracene.

Mar 1, 1947·British Journal of Cancer5.79

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The Relation between Growth Inhibition, Toxicity and Protein Metabolism in Rats Treated with 1:2:5:6-Dibenzanthracene

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The inhibitory action of 1:2:5:6-dibenzanthracene on the growth of the Walker carcinoma 256 in rats maintained on high and low protein diets.

Mar 1, 1947·British Journal of Cancer5.79

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Chemical reactions of the nitrogen mustard gases; the reactions of the nitrogen mustard gases with chemical compounds of biological interest.

Sep 1, 1946·Journal of Organic Chemistry4.33

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CHEMICAL REACTIONS OF THE NITROGEN MUSTARD GASES.1 I. THE TRANSFORMATIONS OF METHYL-BIS(β-CHLOROETHYL)AMINE IN WATER

Sep 1, 1946·Journal of Organic Chemistry4.33

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Chemical reactions of the nitrogen mustard gases; the transformations of methyl-bis(beta-chloroethyl)amine in water.

Sep 1, 1946·Journal of Organic Chemistry4.33

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CHEMICAL REACTIONS OF THE NITROGEN MUSTARD GASES.1 II. THE COMPOSITION OF AGED UNBUFFERED SOLUTIONS OF METHYL-BIS(β-CHLOROETHYL)AMINE

Sep 1, 1946·Journal of Organic Chemistry4.33

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Chemical reactions of the nitrogen mustard gases; the reactions of the nitrogen mustard gases with protein constituents.

Sep 1, 1946·Journal of Organic Chemistry4.33

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Phosphoramide and Oxazaphosphorine Mustards

#1Joel E. WrightH-Index: 1

Phosphoramide mustards and their metabolic precursors, the oxazaphosphorine mustards, belong to the general class of alkylating agents. Some related compounds, the aryl- and alkyl-bis(2-chloroethyl)amines, were covered in the previous chapter. Two oxazaphosphorines, cyclophosphamide and ifosfamide (Fig. 1), are the only phosphorylated mustard compounds ordinarily prescribed for cancer treatment today (1). The developmental work that led to their prominent role in medicine and the outgrowth of pr...more

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Studies on the mechanism of action of cytoxan. Evidence of activation in vivo and in vitro.

Jan 1, 1961·Cancer Research9.73

#1G. E. FoleyH-Index: 2

#2O. M. FriedmanH-Index: 2

Last. B. P. DroletH-Index: 2

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Summary The reported inactivity of Cytoxan, when assayed directly in mammalian cell cultures, has been confirmed, even with cell lines derived from experimental tumors which respond in vivo to Cytoxan therapy. However, blood serum or crude liver extracts from rats treated with Cytoxan were inhibitory in vitro for serially propagated mammalian cells derived from normal or neoplastic tissue, as well as for cells in primary culture. Experiments in which Cytoxan was incubated in vitro in homogenates...more

A study of the inhibition of tumor growth in mice and rats with azo compounds.

May 1, 1952·Cancer5.74

#1Arnold M. Seligman (Harvard University)H-Index: 18

#2Ralph M. Gofstein (Harvard University)H-Index: 4

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Effect of 2-chloro-2'-hydroxydiethyl sulfide (hemisulfur mustard) on carcinomatosis with ascites.

Mar 1, 1952·Cancer5.74

#1Arnold M. Seligman (Harvard University)H-Index: 1

#2Alexander M. Rutenburg (Harvard University)H-Index: 1

Last. Orrie M. Friedman (Harvard University)H-Index: 13

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