Intraocular Pharmacokinetics of Ranibizumab Following a Single Intravitreal Injection in Humans

Purpose To investigate intraocular concentrations and pharmacokinetics of ranibizumab after a single intravitreal injection in humans. Design Prospective, noncomparative, interventional case series. Methods We included 18 nonvitrectomized eyes of 18 patients (age range, 61–85 years) that were diagnosed with both clinically significant cataract and macular edema secondary to either exudative age-related macular degeneration, diabetic maculopathy,...