Molecular pathogenesis of thyroid cancer
Abstract
A number of molecular abnormalities have been described in association with the progression from normal thyroid tissue to benign adenomas to well-differentiated and finally anaplastic epithelial thyroid cancer. These include upregulation of proliferative factors, such as growth hormones and oncogenes, downregulation of apoptotic and cell-cycle inhibitory factors, such as tumor suppressors, disruption of normal cell-to-cell interactions, and...
Paper Details
Title
Molecular pathogenesis of thyroid cancer
Published Date
Aug 1, 2003
Journal
Volume
12
Issue
2
Pages
69 - 90
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Notes
History