Dysferlin is essential for endocytosis in the sea star oocyte
Abstract
Dysferlin is a calcium-binding transmembrane protein involved in membrane fusion and membrane repair. In humans, mutations in the dysferlin gene are associated with muscular dystrophy. In this study, we isolated plasma membrane-enriched fractions from full-grown immature oocytes of the sea star, and identified dysferlin by mass spectrometry analysis. The full-length dysferlin sequence is highly conserved between human and the sea star. We...
Paper Details
Title
Dysferlin is essential for endocytosis in the sea star oocyte
Published Date
Apr 1, 2014
Journal
Volume
388
Issue
1
Pages
94 - 102
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