Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores from Hypericum subsessile

Hypersubones A and B (1, 2), two adamantane type polycyclic polyprenylated acylphloroglucinols possessing an unprecedented seco-adamantane architecture and a tetracyclo-[6.3.1.13,10.04,8]-tridecane core combined with a peroxide ring, respectively, were isolated from Hypericum subsessile together with three analogues (3–5). Their structures were determined by extensive NMR spectroscopic analysis, ECD calculations, and single-crystal X-ray...