PGI2as a Regulator of Inflammatory Diseases
Abstract
Prostacyclin, or PGI(2), is an end product derived from the sequential metabolism of arachidonic acid via cyclooxygenase and PGI synthase (PGIS). The receptor for PGI(2), IP, can be found on a variety of cell types and signaling through this receptor exhibits broad physiological effects. Historically, PGI(2) has been understood to play a role in cardiovascular health, specifically having powerful vasodilatory effects via relaxation of smooth...
Paper Details
Title
PGI2as a Regulator of Inflammatory Diseases
Published Date
Jan 1, 2012
Journal
Volume
2012
Pages
1 - 9
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Notes
History