Grid Laser Photocoagulation After Intravitreal Triamcinolone for Macular Edema Associated With Branch Retinal Vein Occlusion.

Published on May 1, 2009in Journal of The Korean Ophthalmological Society
· DOI :10.3341/JKOS.2009.50.5.704
Seung Uk Lee3
Estimated H-index: 3
(PNU: Pusan National University),
Su Jin Kim2
Estimated H-index: 2
(PNU: Pusan National University)
+ 2 AuthorsBoo Sup Oum19
Estimated H-index: 19
(PNU: Pusan National University)
Sources
Abstract
Purpose: To evaluate the clinical outcomes of macular laser photocoagulation after intravitreal injection of triamcinolone acetonide (IVTA) for macular edema in branch retinal vein occlusion (BRVO). Methods: In this retrospective study we reviewed the medical records of patients who had been treated with an intravitreal injection of 4 mg triamcinolone acetonide for macular edema due to BRVO and followed up for more than six months. We divided the eyes into two groups, namely, the IVTA-only group and the additional grid laser group after IVTA. Visual acuity, macular thickness, intraocular pressure, and abundance of IVTA were compared. Results: A total of 41 eyes underwent IVTA, 21 of which were treated with additional macular grid photocoagulation. The difference in best corrected visual acuity before IVTA between the two groups was not statistically significant. Laser photocoagulation was performed at an average of 2.8 months after IVTA. Final VA and foveal thickness improved significantly after IVTA in both groups and showed no significant difference between the two groups. After six months a second injection was required in six eyes in the IVTA group and one eye in the photocoagulation group due to recurrence of macular edema, the difference of which was significant (p=0.04). Conclusions: IVTA in BRVO patients improved macular edema and visual acuity. Combined grid photocoagulation after IVTA lowered the recurrence rate of macular edema. Grid photocoagulation can be considered as a useful adjuvant for avoiding repeated administration of intravitreal triamcinolone.
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Purpose:To evaluate the efficacy of primary and secondary (following grid laser photocoagulation) intravitreal triamcinolone acetonide (IVTA) injection for the treatment of macular edema associated with branch retinal vein occlusion (BRVO).Methods:Eyes with macular edema secondary to BRVO and best-c
39 CitationsSource
#1Rehák J (Palacký University, Olomouc)H-Index: 6
#2Matus Rehak (Leipzig University)H-Index: 18
In branch retinal vein occlusion (BRVO), abnormal arteriovenous crossing with vein compression, degenerative changes of the vessel wall and abnormal hematological factors constitute the primary mechanism of vessel occlusion. In general, BRVO has a good prognosis: 50–60% of eyes are reported to have a final visual acuity (VA) of 20/40 or better even without treatment. One important prognostic factor for final VA appears to be the initial VA. Grid laser photocoagulation is an established treatment...
294 CitationsSource
#1Sengul Ozdek (Gazi University)H-Index: 21
Last. Berati Hasanreisoglu (Gazi University)H-Index: 23
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Purpose: To evaluate the efficacy of posterior subtenon triamcinolone (PSTT), intravitreal triamcinolone (IVT) injections and grid laser photocoagulation (GLP) in eyes with macular
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#1Joo Youn Oh (SNU: Seoul National University)H-Index: 30
#2Je Hyun Seo (SNU: Seoul National University)H-Index: 11
Last. Hum Chung (SNU: Seoul National University)H-Index: 33
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A few studies on patients with branch retinal vein occlusion (BRVO) have suggested that intravitreal corticosteroid can reduce macular edema and increase visual acuity.1-3 However, these studies did not evaluate the effectiveness of triamcinolone with respect to the timing of the intravitreal injection. In addition, follow-up periods were inadequate or patients who had undergone multiple injections of intravitreal triamcinolone or combined treatment with laser photocoagulation were included. The...
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#1Simon D.M. ChenH-Index: 15
#2Venki SundaramH-Index: 3
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Purpose To evaluate the safety and efficacy of intravitreal triamcinolone acetonide (IVTA) for ischemic macular edema associated with branch retinal vein occlusion (BRVO) and foveal ischemia. Design Prospective interventional case series. Methods setting: Clinical practice. study population: Eighteen eyes of 18 patients with macular edema associated with BRVO and foveal ischemia. intervention: Four mg IVTA. main outcome measures: Visual acuity (VA), optical coherence tomography, macular thicknes...
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#1Henry Lee (WashU: Washington University in St. Louis)H-Index: 1
#2Gaurav K. ShahH-Index: 32
PURPOSE: To describe six patients treated with intravitreal triamcinolone (IVT) as primary therapy for cystoid macular edema (CME) secondary to branch retinal vein occlusion (BRVO). METHODS: Retrospective case series. RESULTS: The age of the patients ranged from 53 years to 87 years (mean, 66 years). The time between BRVO and treatment with IVT ranged from 2.0 months to 4.7 months (mean, 3.5 months). Pretreatment visual acuity ranged from 20/40 to 6/200 (mean, 20/166). Length of follow-up ranged...
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Purpose: To examine the clinical effect of combination method of laser treatment and intravitreal triamcinolone (TA) injection for patient of macular edema with branched retinal vein occlusion (BRVO). Methods: fifteen patients,-(15 eyes), 7 malse and 8 females, with macular edema associated with BRVO were included in the study. The mean age was 59.47 years old. The response to treatment was monitored functionally by visual acuity assessment and anatomically by Optical Coherence Tomography(OCT) f...
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BACKGROUND AND OBJECTIVE: To determine the efficacy of intravitreal triamcinolone acetonide (IVTA) in the early treatment of severe cystoid macular edema (CME) related to acute branch retinal vein occlusion. PATIENTS AND METHODS: Retrospective, non-comparative case series. Twelve eyes with severe CME (foveal thickness > 450 microm) secondary to acute branch retinal vein occlusion received IVTA. RESULTS: Average follow-up was 15.3 months. Mean visual acuity was 0.88 LogMar units (20/160) initiall...
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#1Robert F. Degenring (Heidelberg University)H-Index: 27
#2Bernd A. Kamppeter (Heidelberg University)H-Index: 18
Last. Jost B. Jonas (Heidelberg University)H-Index: 152
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Retinal vein occlusions are common retinal vascular disorders, often complicated by cystoid macular oedema (CMO). The present report describes morphological and functional changes associated with an intravitreal injection of triamcinolone acetonide (TA). Patient 1 was a 75-year-old woman with CMO due to a macular branch vein occlusion 2 years previously. Visual acuity (VA) was reduced to 0.25. Preoperative optical coherence tomography (OCT) and fluorescein angiography (FA) showed a CMO with macu...
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#1Paul M. Beer (Albany Medical College)H-Index: 13
Abstract Purpose To describe the pharmacokinetics occurring after the direct injection of triamcinolone acetonide into the vitreous humor of humans. Design Interventional case series. Participants Five patients who received a single 4-mg intravitreal injection of triamcinolone acetonide. Methods An aqueous humor sample was obtained from 5 eyes via an anterior chamber paracentesis at days 1, 3, 10, 17, and 31 after injection. At each visit, visual acuity and intraocular pressure were measured and...
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