Laminins in basement membrane assembly
Abstract
The heterotrimeric laminins are a defining component of all basement membranes and self-assemble into a cell-associated network. The three short arms of the cross-shaped laminin molecule form the network nodes, with a strict requirement for one α, one β and one γ arm. The globular domain at the end of the long arm binds to cellular receptors, including integrins, α-dystroglycan, heparan sulfates and sulfated glycolipids. Collateral anchorage of...
Paper Details
Title
Laminins in basement membrane assembly
Published Date
Jan 1, 2013
Journal
Volume
7
Issue
1
Pages
56 - 63
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History