Cooperation between cholinergic and glutamatergic receptors are essential to induce BDNF-dependent long-lasting memory storage

The induction of long‐lasting memory storage depends on the behavioral state of humans and animals. This behavioral state is mediated by neuromodulatory systems, like the cholinergic–septum–hippocampal circuit. Cholinergic neurotransmission is known to affect short‐term activity‐dependent plasticity in various brain areas, including the hippocampus. We could show here that a chemical late‐long‐term potentiation (LTP) could be induced in the...