Original paper
Pirfenidone suppresses keloid fibroblast-embedded collagen gel contraction
Volume: 304, Issue: 3, Pages: 217 - 222
Published: Oct 28, 2011
Abstract
Keloid is a clinically intractable disease that causes disfigurement, itching, and pain due to abnormal proliferation of fibroblasts and production of collagen. Pirfenidone is a novel anti-fibrotic agent that inhibits the progression of fibrosis occurring in the keloid lesions of the lung and kidney. In order to examine whether pirfenidone has a therapeutic effect on keloid lesions, we prepared an in vitro wound contraction model with keloid...
Paper Details
Title
Pirfenidone suppresses keloid fibroblast-embedded collagen gel contraction
Published Date
Oct 28, 2011
Volume
304
Issue
3
Pages
217 - 222
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History