Importance of mesenchymal stem cells in autologous fat grafting: A systematic review of existing studies

Autologous fat grafting (lipofilling) enables repair and augmentation of soft tissues and is increasingly used both in aesthetic and reconstructive surgery. Autologous fat has several advantages, including biocompatibility, versatility, natural appearance, and low donor site morbidity. The main limitation is unpredictable graft resorption, which ranges from 25%–80%, probably as a result of ischaemia and lack of neoangiogenesis. To obviate these...