Interstitial Fluid Pressure Surrounding Rat Mesenteric Venules During Changes in Fluid Filtration

The interstitial fluid pressure ( P isf ) has been measured in the exposed superfused mesenteries of anaesthetised rats using the micropipette servo‐null technique. When mesenteries were superfused with Ringer‐Locke solutions, P isf was close to atmospheric pressure with mean ± S.E.M. values of ‐0.46 ± 0.14 cmH 2 O ( n = 22). Superfusing with paraffin oil did not alter P isf significantly, but P isf could be lowered considerably by removing...