Hairless Guinea Pig Bioassay Model for Vesicant Vapor Exposures

Volume: 15, Issue: 3, Pages: 622 - 630
Published: Oct 1, 1990
Abstract
null null Sulfur mustard (HD; 1,1′-thiobis[2-chloroethane]) induces fluid-filled blisters in man but not in conventional laboratory animals. An animal model is needed to emulate both cytotoxic (vesicant) and vascular (irritant) responses of human skin to HD exposures. An acceptable model must permit reproducible comparisons of uniformly graded and dose-related HD control responses with reduced responses that may follow antivesicant treatments....
Paper Details
Title
Hairless Guinea Pig Bioassay Model for Vesicant Vapor Exposures
Published Date
Oct 1, 1990
Volume
15
Issue
3
Pages
622 - 630
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