Systems biology of interstitial lung diseases: integration of mRNA and microRNA expression changes

The molecular pathways involved in the interstitial lung diseases (ILDs) are poorly understood. Systems biology approaches, with global expression data sets, were used to identify perturbed gene networks, to gain some understanding of the underlying mechanisms, and to develop specific hypotheses relevant to these chronic lung diseases.Lung tissue samples from patients with different types of ILD were obtained from the Lung Tissue Research...