Polymyxin B-Immobilized Fiber Hemoperfusion Attenuates Increased Plasma Atrial Natriuretic Peptide and Brain Natriuretic Peptide Levels in Patients With Septic Shock

Polymyxin B-immobilized fiber (PMX-F) hemoperfusion is reported to be safe and effective in septic shock patients. Because atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) may have pathophysiologic significance in the cardiac dysfunction of septic shock patients, we conducted a study to determine whether PMX-F treatment affects plasma ANP and BNP levels in patients with septic shock. Fifty septic shock patients (34 men and 16...