Studies on the relationships between the immunogenicity and catabolism of antigens and their binding to the surface of macrophages

The relationship between immunogenicity of Shigella paradysenteriae , the branched synthetic polypeptide poly‐ L (Tyr, Glu)‐poly L Pro‐poly L Lys [(T, G)‐Pro–L] and human serum albumin (HSA) interacting with macrophages and the kinetics of antigen degradation and degree of binding to the cell surface was studied. Following thioglycollate inoculation into C57BL/6 mice, the peritoneal‐stimulated macrophages had higher levels of hydrolases as...