Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat
Abstract
Iodoacetic acid (IAA) has been applied to different species to acutely induce photoreceptor degeneration. The purpose of the present study was to use this toxin to thoroughly eliminate photoreceptors and induce complete blindness in the cat. IAA was delivered by single ear vein injection (20 mg kg(-1)). Six months after the IAA treatment, functional evaluations including pupillary light reflex (PLR), electroretinogram (ERG), visual behavior...
Paper Details
Title
Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat
Published Date
May 8, 2013
Journal
Volume
56
Issue
6
Pages
524 - 530
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