We present a case of granulomatous prostatitis that presented in a rare way as an incidentally discovered focus of increased FDG activity within the prostate on PET-CT in a patient who had previously undergone intravesical bacille Calmette-Guerin treatment for bladder cancer. FDG uptake is commonly discovered in organs distant from the region of primary interest on PET-CT and so it is important to be aware of the potential causes of this.
With the increasing utilization of integrated positron-emission tomography/computed tomography (PET/CT) using the glucose analogue 2-[18F]-fluoro-2-deoxy- d- glucose (FDG) in oncological imaging, it is important for radiologists and nuclear medicine physicians to be aware that FDG uptake is not specific for malignancy, as many different physiological variants and benign pathological conditions can also exhibit increased glucose metabolism. Such false-positive FDG uptake often arises outside the ...
To evaluate the clinical significance of incidental focal prostate fluorodeoxyglucose (FDG) uptake, we reviewed 18-F-FDG positron emission tomography (PET)/CT scans from 2003 to 2007 and selected cases with focal FDG uptake in prostate. Cases of known prostate cancer were excluded. The maximum standardised uptake value (SUVmax), site (central or peripheral) and pattern (discrete or ill-defined) of FDG uptake, calcification (present or absent) and prostate volume (<30 or ≥30 cc) were recorded. Th...
Background Despite a paucity of evidence-based guidelines, the use of PET/CT (positron emission tomography/computed tomography) in the management of cancer patients is increasing. As widespread clinical application increases, unexpected radiographic findings are occasionally identified. These incidental findings are often suspicious for a second primary malignancy. The purpose of this study was to determine the clinical impact of these incidental PET/CT findings. Methods A query of our prospecti...
OBJECTIVE. The objective of our study was to characterize benign lesions showing increased 18F-FDG uptake and to determine their incidence on whole-body FDG PET/CT performed in oncologic patients. In addition, the performance of PET alone and PET/CT in characterizing lesions as benign was compared.MATERIALS AND METHODS. A retrospective review of 1,134 consecutive reports of PET/CT studies performed in patients with proven or suspected malignancy over a 6-month period yielded 289 patients with 31...
Abstract Granulomatous prostatitis is a benign inflammatory condition of the prostate which can be mistaken for prostatic carcinoma both clinically and on imaging findings. In MR imaging, granulomatous prostatitis has been shown to cause signal intensity decrease in the prostatic peripheral zone similar to carcinoma on T2-weighted sequences. The recent introduction of 3D MR spectroscopy (3D MRS) into clinical practice adds information to the morphological data of endorectal MRI, enabling a more ...
The first paper in this section is a meta-analysis of randomized trials into the effect of two intravesical agents used to reduce tumour recurrence in high-risk superficial bladder cancer. This is the highest level of evidence-based medicine and the results presented here suggest that intravesical BCG is superior to mitomycin C. There was no difference in the effect of the two agents on disease progression or survival. In a study from Amsterdam and Rome, the authors describe a phase I trial into...
Bacille Calmette-Guerin (BCG) immunotherapy is currently considered the most effective agent in the management of superficial bladder cancer. Prior work suggests that the efficacy of intravesical chemotherapy in preventing tumor recurrence may be greater than previously suggested. This latter finding, therefore, brings into question the currently perceived superiority of BCG treatment for this disease. A metaanalysis was performed to rigorously examine existing data relevant to this relationship...
Positron emission tomography (PET) is routinely used in the management of cancers such as lung, colorectal, esophageal, breast, lymphoma, and melanoma. In urologic oncology, the role of PET has been less well defined and is currently under investigation. We report the first case of PET scan detection of prostate cancer in a patient with Hodgkins lymphoma. (received 25 April 2003, accepted 15 May 2003)
AbstractA 45-year-old man underwent FDG PET/CT for initial imaging evaluation of recurrent Escherichia coli urinary tract infections, which demonstrated no significant FDG uptake in either kidney and subtle FDG uptake in the right prostate lobe. Subsequent 67Ga SPECT/CT demonstrated abnormal intense
Het doel van deze studie was het bepalen van de klinische relevantie van incidentele prostaatopname (IPO) op een FDG-PET/CT-scan. We analyseerden 108 mannelijke patienten met blaascarcinoom (BCa) die een FDG-PET/CT-scan ondergingen en vervolgens een cystoprostatectomie, in de periode 2009–2014. IPO had een slechte voorspellende waarde voor de aanwezigheid van prostaatcarcinoom (PCa). Diagnostische nauwkeurigheid verbeterde niet wanneer een nucleair geneeskundige de laesies classificeerde op basi...
Purpose: FDG (18F-fluoro-2-deoxy-D-glucose)-PET/CT (positron emission tomography)/(computerized tomography) is a widely used diagnostic tool for whole body imaging. Incidental prostatic uptake is often found on FDG-PET/CT. The objective of this study was to determine the clinical relevance of incidental prostatic uptake on FDG-PET/CT.Materials and Methods: We analyzed 108 consecutive male patients with bladder cancer who underwent FDG-PET/CT and subsequently radical cystoprostatectomy between Ma...
#1Choon-Young Kim(KNU: Kyungpook National University)H-Index: 10
#2Sang-Woo Lee(KNU: Kyungpook National University)H-Index: 28
Last. Jaetae Lee(KNU: Kyungpook National University)H-Index: 30
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Purpose This study aimed to evaluate the possibility that Bacillus Calmette-Guerin (BCG)-induced granulomatous prostatitis can be a potential cause of benign F-18 FDG uptake.
Incidental prostate uptake of fl uorine-18-fl uorodeoxyglucose in positron emission tomography/computed tomography ( 18 F-FDG PET/CT) may represent malignancies like prostate malignancy, infl ammation or benign prostatic lesions. We report two cases of bacillus Calmette-Guerin (BCG)-induced granulomatous prostatitis that showed 18 F-FDG uptake of the prostate gland on 18 F-FDG PET/CT in patients who had previously received intravesical BCG treatment for bladder cancer. The degree of 18 F-FDG upt...
Abstract Objective The objective was to investigate the prevalence of incidental fluorine-18 fluorodeoxyglucose (FDG) uptake in positron emission tomography/computed tomography. Methods A total of 11,239 male nonprostate disease patients were included retrospectively. Results The prevalence of incidental prostate FDG uptake was approximately 1.8%. Among 198 incidental lesions, 100 patients had further examinations; 20 lesions were confirmed to be malignant, while 80 lesions were benign. After lo...
#1Aisheng Dong('SMMU': Second Military Medical University)H-Index: 12
#2Yushu Bai('SMMU': Second Military Medical University)H-Index: 5
Last. Jianping Lu('SMMU': Second Military Medical University)H-Index: 16
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Objective Increased FDG uptake in the prostate can be caused by both benign and malignant conditions. The purpose of this pictorial review is to demonstrate a spectrum of prostate lesions which can show increased FDG uptake on PET/CT imaging.
Aim: To perform a systematic review and meta-analysis of published data on the prevalence and risk of malignancy of prostatic incidental uptake (PIU) detected by fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) or PET/computed tomography (PET/CT). Patients, material, methods: A comprehensive literature search of studies published up to February 2014 was performed. Pooled prevalence and malignancy risk of PIU were calculated on a per patient-based analysis including 95%...
Aim: To perform a systematic review and meta-analysis of published data on the prevalence and risk of malignancy of prostatic incidental uptake (PIU) detected by fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) or PET/computed tomography (PET/CT). Patients, material, methods: A comprehensive literature search of studies published up to February 2014 was performed. Pooled prevalence and malignancy risk of PIU were calculated on a per patient-based analysis including 95%...