HLA-allelotype associations with nevirapine-induced hypersensitivity reactions and hepatotoxicity

Various studies have investigated associations between immunogenetic (HLA-allelotypes) factors and the risk of nevirapine-induced hypersensitivity reactions. However, results from individual studies have been inconsistent. To evaluate the association between HLA alleles and nevirapine hypersensitivity, a systematic review and meta-analysis was carried out.A literature review of articles published up to December 2014 was performed. Where both...