Mast Cell Degranulation is Essential for Anastomotic Healing in Well Perfused and Poorly Perfused Rat Colon

Background Mast cell degranulation is an important step in early wound healing in the skin however the role of the mast cell in anastomotic healing is less clear. The aim of this study was to investigate the importance of mast cell degranulation in anastomotic healing and to assess whether a promoter of mast cell degranulation could increase anastomotic healing in poorly perfused bowel. Methods Fifty Wistar rats were divided into five groups:...