Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives
Abstract
Catechin derivatives with different alkyl chain length and aromatic ring substitutions at the 3-hydroxyl group were synthesized from epigallocatechin (EGC) and (+)-catechin (C) and their anti-influenza viral activity were evaluated in vitro and in ovo. Pronounced antiviral activity was observed for derivatives carrying moderate chain length (7-9 carbons) as compared to those with aromatic rings, whereas the 5'-hydroxyl group of the trihydroxy...
Paper Details
Title
Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives
Published Date
Nov 1, 2007
Journal
Volume
76
Issue
2
Pages
178 - 185
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