Bisphenol A impairs mitochondrial function in spleens of mice via oxidative stress

Increasing evidences show that bisphenol A(BPA) affects immune responses, which the mechanism is mainly regarded as estrogenic effect on a variety of immune cells. Besides its estrogenic activity, BPA can cause oxidative damage of liver, kidneys and brain. Due to limited information concerning the effect of BPA on spleen, a principle site for initiation of primary immune responses, especially no data are available on its actions on the...