Role of natural antioxidants and potential use of bergamot in treating rheumatoid arthritis

The aim of the present review is to report about the effect of natural compounds, with proved antioxidant activity and mainly introduced with diet, on rheumatoid arthritis (RA). RA is a chronic, systemic inflammatory disorder leading to cartilage damage, bone erosions, joint destruction and impaired movement. The pathophysiology of RA includes reactive oxygen species (ROS) production, which is concomitant with inflammation and provokes a wide...