High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes
Abstract
Screening gene function in vivo is a powerful approach to discover novel drug targets. We present high-throughput screening (HTS) data for 3 762 distinct global gene knockout (KO) mouse lines with viable adult homozygous mice generated using either gene-trap or homologous recombination technologies. Bone mass was determined from DEXA scans of male and female mice at 14 weeks of age and by microCT analyses of bones from male mice at 16 weeks of...
Paper Details
Title
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes
Published Date
Oct 28, 2014
Journal
Volume
2
Issue
1
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