Orodigitofacial dysostosis—a new syndrome

Orodigitofacial dysostosis occurs in approximately 1 in 100 patients with cleft palate and has so far been seen only in females. The most common manifestations are hyperplasia of the frenula, a cleft tongue, and cleft palate. Less commonly there is absence of the lower lateral incisors, alopecia or dryness of the hair, anomalies of the facial or cranial bones, anomalies of the hands, or mental retardation. Orodigitofacial dysostosis occurs in...