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Neonatal Abstinence Syndrome after Methadone or Buprenorphine Exposure
Volume: 363, Issue: 24, Pages: 2320 - 2331
Published: Dec 9, 2010
Abstract
Methadone, a full mu-opioid agonist, is the recommended treatment for opioid dependence during pregnancy. However, prenatal exposure to methadone is associated with a neonatal abstinence syndrome (NAS) characterized by central nervous system hyperirritability and autonomic nervous system dysfunction, which often requires medication and extended hospitalization. Buprenorphine, a partial mu-opioid agonist, is an alternative treatment for opioid...
Paper Details
Title
Neonatal Abstinence Syndrome after Methadone or Buprenorphine Exposure
Published Date
Dec 9, 2010
Volume
363
Issue
24
Pages
2320 - 2331
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