Targeted proteomics strategy applied to biomarker evaluation

The evaluation of biomarker candidates, involving quantitative measurement of a large number of proteins in bodily fluids, remains the main obstruction in the development of a biomarker validation pipeline. Although immunoassays are commonly used, high‐throughput and multiplex‐capable methods are required for expediting the evaluation process. MS‐based approaches employing targeted proteomic strategies provide not only a sensitive, but in...