PHYSICOCHEMICAL PROPERTIES AND ANTIBACTERIAL ACTIVITY OF THE PRECIPITATE OF VANCOMYCIN AND CEFTAZIDIME

In Brief Objective: To study the physicochemical properties, bioavailability, and microbicidal activity of vancomycin and ceftazidime in the precipitate formed by the drugs in mixture. Methods: The precipitation of the drugs prepared in buffers in the pH range of 5.8 to 8.9, in normal saline, in balanced salt solution (BSS), and in Ringer lactate, was studied by light scatter analysis. Bioavailability and antibacterial activity of the...