Purpose
To investigate relationships between age, weight, refractive error, and morphologic changes in children's eyes by computerized tomography (CT).
An epidemiological study of the prevalence of refractive errors was made of the Eskimo population of the Norton Sound and Bering Straits region of Alaska. It was possible to determine the subjective refraction in 83.7% of 1673 persons examined: 44.9% were emmetropic, 44.7% myopic and 10.4% hyperopic. Myopia was found more often in women (48.3%) than in men (41.3%), while emmetropia was found more often in men (49.3%) than in women (40.3%). Nine,four percent of the men were hyperopic and 11.4% of...
Method ‘A’ ultrasonographic biometry was perfomed on 23 patients with congenital glaucoma. The axial lengths of these eyes were significantly greater as compared to the 7 fellow eyes with normal intraocular pressures of the same patients and 10 eyes of 5 patients with megalocornea of the same age. Some of the borderline cases showed an increase of axial length during follow-up not attributable to normal growth. After successful surgery an early decrease of the axial length up to 0.8 mm could be ...
The corneal thickness of 108 human subjects, ranging from 17 to 75 years of age, was measured using ultrasound pachometry. One central, four mid-peripheral and four peripheral corneal positions along the vertical and horizontal meridians were assessed using ultrasound pachometry. No significant differences were found in the thicknesses of the central, midperipheral or peripheral cornea with increasing age using analysis of variance. These results suggest that ageing has no significant effect on ...
The central thickness of the left eyes of 1082 New Zealand students aged 5 to 20 years were measured using optical pachometry No significant variation in corneal thickness was found with increasing age The mean corneal thickness of the left eye was 540±25 μm No significant differences in corneal thickness were found when the effects of sex or cultural groupings were examined Corneal thickness appears to remain constant between the age of 5 and 20 years, irrespective of sex or cultural grouping
The results of the ultrasonographic measurements of the ocular components in 40 emmetropic eyes from men of nearly the same age are presented and the possible relation between the axial eye length and the head size is discussed. A significant correlation was found between the axial eye length and the head circumference (P < 0.001), between the axial eye length and the head length (P < 0.01) and between the axial eye length and the head breadth (P < 0.02). A significant correlation was also found...
Congenital microphthalmos and anophthalmos are currently considered rare conditions. Many infectious agents have been previously associated with these pathologies, but rarelyTreponema pallidum. We report a case of bilateral microphthalmos in which her mother presented gestational syphilis.
Purpose: (1) To find out the relationship of the depth of amblyopia with the degree of anisometropia, in untreated cases of anisometropic amblyopia without strabismus, for both myopic and hypermetropic individuals. (2) To find out the relationship between various ocular parameters, such as axial length and corneal curvature, with the degree of anisometropia between the two eyes. Materials and Methods: This prospective study was conducted between January 2001 and March 2003, in 85 cases of untrea...
Last. Richard A. Stone(UPenn: University of Pennsylvania)H-Index: 61
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Aims: To assess the longitudinal changes in biometric parameters and associated factors in young myopic children aged 7–9 years followed prospectively in Singapore. Methods: Children aged 7–9 years from three Singapore schools were invited to participate in the SCORM (Singapore Cohort study Of the Risk factors for Myopia) study. Yearly eye examinations involving biometry measures were performed in the schools. Only myopic children (n = 543) with 3 year follow up data were included in this analys...
Last. Karla Zadnik(OSU: Ohio State University)H-Index: 71
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PURPOSE. To evaluate the contribution made by the ocular components to the emmetropization of spherical equivalent refractive error in human infants between 3 and 9 months of age. METHODS. Keratophakometry in two meridians was performed on 222 normal-birthweight infant subjects at 3 and 9 months of age. The spherical equivalent refractive error was measured by cycloplegic retinoscopy (cyclopentolate 1%). Anterior chamber depth, lens thickness, and vitreous chamber depth were measured by A-scan u...
#2Paul N. Orloff(Manhattan Eye, Ear and Throat Hospital)H-Index: 1
Purpose A thin central cornea has been reported to be a risk factor for developing primary open-angle glaucoma among ocular hypertensive eyes. A thin scleral bed of lamina cribrosa seen in deeply excavated optic nerves in glaucomatous eyes is a quintessential finding in advanced glaucomatous eyes. Association between thin cornea and weak sclera contributing to vulnerability of lamina cribrosa has been postulated. The purpose of this study is to determine whether there is an association between c...
We investigated the change in the retinal gas cover rates due to intraocular gas volume and positions using computational eye models and demonstrated the appropriate position after pars plana vitrectomy (PPV) with gas tamponade for rhegmatogenous retinal detachments (RRDs). Computational fluid dynamic (CFD) software was used to calculate the retinal wall wettability of a computational pseudophakic eye models using fluid analysis. The model utilized different gas volumes from 10 to 90%, in increm...
Here, we explore the effects of prenatal alcohol exposure (PAE) in adolescence. We investigated associations between meconium ethyl glucoronide (EtG) and facial malformation. For 129 children (66/63 male/female; M = 13.3, SD = 0.32, 12–14 years), PAE was implemented by newborn meconium EtG and maternal self-reports during the third trimester. Cognitive development was operationalized by standardized scores (WISC V). The EtG cut-off values were set at ≥10 ng/g (n = 32, 24.8% EtG10+) and ≥112 ng/g...
Knobloch Syndrome (KS) is a rare autosomal recessive hereditary disease. Despite its clinical heterogeneity, it is characterized by vitreoretinal degeneration and high myopia, with or without occipital skull defects. It is caused by mutations in the COL18A1 gene, which codifies for collagen XVIII, present in retina and vascular endothelium. Since the first description of the disease by doctors Knobloch and Layer in 1972, over 100 cases and 20 pathogenic or likely pathogenic mutations have been r...
Amac; Bulbus oculi’ye ait cap ve yukseklik olcumleri ile klinik onemini vurgulamaktir. Gerec ve Yontem; 19-68 yas arasi 110 kadin ve 80 erkek olmak uzere toplam 190 bireyin magnetik rezonans goruntuleri kullanilarak retrospektif bir calisma yapilmistir. Calismamizda bulbus oculi’ye ait sag ve sol tarafta antero-posterior cap, transvers cap ve yukseklik olcumleri yapilmistir. Bulgular; Yas ortalamasi 36,71 olan 110 kadin ve yas ortalamasi 36,79 olan 80 erkek katilimcida Bulbus oculi AP Cap (Sag),...
Last. Mehmet Keskin(University of Gaziantep)H-Index: 10
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Background The olfactory bulb (OB) and eyeball size change depending on age and puberty. There is a well-established trade-off between sensory structures of the brain such as the eye and the olfactory bulb that depend on environmental circumstances in the evolutionary history of animals. The aim of this study was to developmentally investigate the potential reciprocal changes between OB and eyeball volumes (EV) in girls with precocious puberty (PP). Methods A total of 148 girls aged between 5 an...
#1Anquan Xue(WMU: Wenzhou Medical College)H-Index: 5
#2Linyan Zheng(WMU: Wenzhou Medical College)H-Index: 1
Last. Jia Qu(WMU: Wenzhou Medical College)H-Index: 61
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Purpose: Myopia has become a global public health problem, particularly in East Asia where myopic retinopathy has become one of the leading causes of blindness and visual impairment in the elderly population. The purpose of this study was to evaluate the efficacy of posterior scleral contraction/reinforcement (PSCR) surgery on controlling the progressive elongation of axial length of highly myopic eyes in young patients. Methods: This is a prospective self-controlled interventional case series. ...
Last. Reza Dana(MEE: Massachusetts Eye and Ear Infirmary)H-Index: 86
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Corneal thickness is tightly regulated by its boundary endothelial and epithelial layers. The regulated set-point of corneal thickness likely shows inter-individual variations, changes by age, and response to stress. Using anterior segment-optical coherence tomography, we measure murine central corneal thickness and report on body size scaling of murine central corneal thickness during aging. For aged-matched mice, we find that corneal thickness depends on sex and strain. To shed mechanistic ins...
The primary aim of this thesis was to investigate in-vivo changes to ocular morphology during ocular accommodation, with particular attention to ciliary muscle changes, using pharmacological agents and physiological stimuli. To determine the optimum target for accommodation studies, accommodative responses to different stimuli were investigated. Insignificant differences in accommodative responses to a letter target and Maltese cross were found. Anterior Segment Optical Coherence Tomography (AS-...
PURPOSE: To determine the association between changes in body length with ocular refraction, corneal radii, axial length, and lens thickness in two different mouse strains. METHODS: Body length, ocular refraction, corneal radii, axial length, and lens thickness were measured for two inbred mouse strains: 129S1/SvJ (n = 7) and C57BL/6 J (n = 10) from 4 to 12 weeks of age. Body length, from tip of nose to base of tail, was obtained using a digital camera. Biometric parameters, corneal radii, and r...
to perform a comparative study of peripheral refraction and retinal contour in patients with congenital versus acquired high myopia.A total of 30 patients (60 eyes) with high myopia aged 8 to 18 years (11.2±0.32 years on average) were examined. The patients were divided into 2 groups. Group 1 consisted of 21 patients (42 eyes) with acquired myopia of -6.0 to -10.25 diopters (-7.55±0.17 diopters on average), group 2 - of 9 patients (18 eyes) with congenital myopia of -8.75 to -28.75 diopters (-16...