Original paper
Generic anti-drug antibody assay with drug tolerance in serum samples from mice exposed to human antibodies
Abstract
Knowledge of the anti-drug antibody (ADA) status is necessary in early research studies. Because specific assay materials are sparse and time is pressing, a generic assay format with drug tolerance for detection of ADAs in serum samples from mice exposed to immunoglobulin G (IgG) or antigen-binding fragments (Fabs) is highly desirable. This article describes a generic immune complex assay in the sandwich enzyme-linked immunosorbent assay (ELISA)...
Paper Details
Title
Generic anti-drug antibody assay with drug tolerance in serum samples from mice exposed to human antibodies
Published Date
Nov 1, 2012
Journal
Volume
430
Issue
2
Pages
193 - 199
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Notes
History