Global Diastolic Strain Rate for the Assessment of Left Ventricular Relaxation and Filling Pressures

Background— Diastolic strain rate (SR) measurements that comprise all left ventricular (LV) segments are advantageous over myocardial velocity for assessment of diastolic function. Mitral early diastolic velocity (E)/SR ratio during the isovolumetric relaxation (IVR) period can be used to estimate LV filling pressures. Methods and Results— Simultaneous echocardiographic imaging and LV pressure measurements (7F catheters) were performed in 7...