Review paper
Infantile Malignant, Autosomal Recessive Osteopetrosis: The Rich and The Poor
Abstract
Human recessive osteopetrosis (ARO) represents a group of diseases in which, due to a defect in osteoclasts, bone resorption is prevented. The deficit could arise either from failure in osteoclast differentiation or from inability to perform resorption by mature, multinucleated, but nonfunctional cells. Historically, osteopetrosis due to both these mechanisms was found in spontaneous and artificially created mouse mutants, but the first five...
Paper Details
Title
Infantile Malignant, Autosomal Recessive Osteopetrosis: The Rich and The Poor
Published Date
Dec 12, 2008
Volume
84
Issue
1
Pages
1 - 12
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History