Original paper
Potential new targets involved in 1,3-dinitrobenzene induced testicular toxicity
Abstract
1,3-Dinitrobenzene (DNB) causes testicular injury, particularly to Sertoli cells, and induces apoptosis in the surrounding germinal cells in rodents; however, the mechanisms causing this toxicity are poorly understood. Our studies, using standard and molecular tools, were conducted to better understand the pathogenesis of the testicular effects. Four daily oral doses of 0.1–8 mg/kg/day caused marked testicular lesions in rats from 4 mg/kg/day....
Paper Details
Title
Potential new targets involved in 1,3-dinitrobenzene induced testicular toxicity
Published Date
Sep 1, 2012
Journal
Volume
213
Issue
2
Pages
275 - 284
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Notes
History