B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease

Volume: 74, Issue: 12, Pages: 2236 - 2243
Published: Dec 1, 2015
Abstract
Objectives null Fibrosis is a predominant feature of IgG4-related disease (IgG4-RD). B-cell depletion induces a prompt clinical and immunological response in patients with IgG4-RD, but the effects of this intervention on fibrosis in IgG4-RD are unknown. We used the enhanced liver fibrosis (ELF) score to address the impact of rituximab on fibroblast activation. The ELF score is an algorithm based on serum concentrations of procollagen-III...
Paper Details
Title
B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease
Published Date
Dec 1, 2015
Volume
74
Issue
12
Pages
2236 - 2243
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