Original paper
Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides
Abstract
Bis-2,3-heteroarylmaleimides and polyheterocondensed imides joined through nitrogen atoms of the N,N'-bis(ethyl)-1,3-propanediamine linker were prepared from substituted maleic anhydrides and symmetrical diamines in good to satisfactory yields and short reaction times using microwave heating. The novel molecules were shown to inhibit proliferation of human tumor cells (NCI-H460 lung carcinoma) and rat aortic smooth muscle cells (SMCs) with...
Paper Details
Title
Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides
Published Date
Sep 1, 2011
Volume
19
Issue
18
Pages
5291 - 5299
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Notes
History