Relentless placoid chorioretinitis.

Published on Jan 1, 2012in International Ophthalmology Clinics
· DOI :10.1097/IIO.0B013E31826686A3
Rukhsana G. Mirza11
Estimated H-index: 11
Lee M. Jampol78
Estimated H-index: 78
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The white dot syndromes (WDSs) comprise a heterogeneous group of posterior uveitic syndromes characterized by multiple lesions of the posterior pole due to inflammation of the choroid, retinal pigment epithelium (RPE), and retina.1,2 The WDSs classically include acute posterior multifocal placoid pigment epitheliopathy (APMPPE), serpiginous choroidopathy (SPC), birdshot retinochoroidopathy (BRC), multiple evanescent white dot syndrome (MEWDS), and multifocal choroiditis (MFC). Other conditions s...
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The purpose of this study was to report the clinical profile and management of patients with serpiginous choroiditis in a tertiary care referral center in India. In a retrospective cohort study, 107 eyes of 70 patients with serpiginous choroiditis seen between January 1995 and December 2002 were analyzed. Systemic steroids and immunosuppressives were the mainstay of therapy. Antituberculous and antiviral drugs were used in selected cases. There was male preponderance (7:3). Age at presentation r...
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Abstract Setting: The granulomatous uveitis, multifocal choroiditis and periphlebitis have been suspected to be of tubercular origin but no definitive reports about detection of etiological agents have been documented in the literature. Conventional bacteriological methods are not generally helpful in diagnosing ocular tuberculosis due to difficulty with potential morbidity associated with obtaining the biopsy material from the eye. Thus, the diagnosis of ocular tuberculosis is most often presum...
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Acute posterior multifocal placoid pigment epitheliopathy recurred in seven patients (all men, ranging in age from 25 to 43 years). In all seven cases swelling of the pigment epithelium resolved rapidly but left a permanent pigmentary disturbance. Loss of choriocapillaris occurred in six cases. Three patients had severe unilateral visual loss. Three patients had used antimicrobial drugs (two of them repeatedly), suggesting that in some cases this condition may be a manifestation of a hypersensit...
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#1R. Rishi Gupta (Dal: Dalhousie University)H-Index: 4
#2Douglas S. M. Iaboni (Dal: Dalhousie University)H-Index: 3
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Purpose:We report a case of relentless placoid chorioretinitis (RPC) that developed branch retinal vein occlusion and peripheral retinal neovascularization in one eye.Methods:A case report is prese...
#1Alessandro MarcheseH-Index: 11
#2Aniruddha Agarwal (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 23
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Placoid lesions of the retina may be secondary to a wide spectrum of acquired inflammatory conditions that have been reported as single entities with different presentation and clinical course. These conditions include acute posterior multifocal placoid pigment epitheliopathy, persistent placoid maculopathy, serpiginous choroiditis, serpiginous-like choroiditis, relentless placoid chorioretinitis and acute syphilitic posterior placoid chorioretinitis. In this article, we will group these conditi...
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#1Takehiko Uraki (Hokkaido University)H-Index: 2
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Abstract Purpose Relentless placoid chorioretinitis (RPC) is a new disease concept that was proposed by Jones et al. in 2000. Some cases of RPC have been reported; however, a treatment strategy has not yet been established. We report herein four cases of patients diagnosed with RPC. Observations We experienced four cases of RPC in patients aged 24–51 years. All patients exhibited retinal lesions similar to that seen in acute posterior multifocal placoid pigment epitheliopathy or serpiginous chor...
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ABSTRACTPurpose: To report the first case of stroke in a patient with relentless placoid chorioretinitis.Methods: Observational case report.Results: A 20-year-old female with newly diagnosed relentless placoid chorioretinitis was urgently evaluated for unilateral paresthesias. She was found to have acute bilateral pontine strokes and cerebral vasculitis on magnetic resonance imaging of the brain and cerebral angiography.Conclusions: We report the first case of stroke due to cerebral vasculitis i...
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The white dot syndromes (WDS) are a diverse group of posterior uveitidies that share similar clinical findings but are unique from one another. Multimodal imaging has allowed us to better understand the morphology, the activity and age of lesions, and whether there is CNV associated with these different ocular pathologies. The “white dot syndromes” and their uveitic masqueraders can now be anatomically categorized based on lesion localization. The categories include local uveitic syndromes with ...
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#1Stephanie M. Llop (MEE: Massachusetts Eye and Ear Infirmary)H-Index: 2
Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) is an inflammatory choroidal disease that is included in the differential diagnosis of the white dot syndromes. This condition is usually bilateral and characterized by creamy-yellow or white subretinal lesions at the level of the Retinal Pigment Epithelium (RPE) and choriocapillaris that mostly involve the posterior pole. It has a predilection for young, healthy adults and has been associated with many infectious and non-infecti...
#1Carl P. Herbort (UNIL: University of Lausanne)H-Index: 46
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) like other inflammatory entities of the choriocapillaris was included in the purely descriptive pot-pourri group of white dot syndromes, a classification that nowadays has no reason to be maintained. As for many fundus diseases, it was J. Donald M. Gass who first described the disease in 1968. He called the disease acute posterior multifocal placoid pigment epitheliopathy (APMPPE) because he thought that the disease was due to an...
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#1Luca Cimino (UNIL: University of Lausanne)H-Index: 1
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Between 1968 and 1984, several diseases of the fundus were newly described. APMPPE was first reported by Donald Gass in 1968 [1]. The primary inflammatory target of the disease was attributed by him to the retinal pigment epithelium (RPE).
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