CHANGES IN FUSED CELLS INDUCED BY HVJ (SENDAI VIRUS): RELATIONSHIP OF MORPHOLOGICAL CHANGES TO ENDOCYTOSIS OF THE SURFACE MEMBRANE

Fused Ehlrich ascites tumor (EAT) cells induced by hemagglutinating virus of Japan (HVJ; Sendai virus) had an irregular shape, reflecting the shape of cell aggregates before fusion. During subsequent culture, the fused cells gradually took on a spherical form within 60 min. Examination of the fused cells revealed a vigorous endocytosis of the cell membrane during the morphological change. When EAT cells were treated with porphyrin derivatives,...