Original paper
Type I interferons induce autophagy in certain human cancer cell lines
Abstract
Autophagy is an evolutionarily conserved cellular recycling mechanism that occurs at a basal level in all cells. It can be further induced by various stimuli including starvation, hypoxia, and treatment with cytokines such as IFNG/IFNγ and TGFB/TGFβ. Type I IFNs are proteins that induce an antiviral state in cells. They also have antiproliferative, proapoptotic and immunomodulatory activities. We investigated whether type I IFN can also induce...
Paper Details
Title
Type I interferons induce autophagy in certain human cancer cell lines
Published Date
May 6, 2013
Journal
Volume
9
Issue
5
Pages
683 - 696
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Notes
History