Surface characteristics and fibroblast adhesion behavior of RGD-immobilized biodegradable PLLA films

The interactions between the surface of scaffolds and specific cells play an important role in tissue engineering applications. Some cell adhesive ligand peptides including Arg-Gly-Asp (RGD) have been grafted into polymeric scaffolds to improve specific cell attachment. In order to make cell adhesive scaffolds for tissue regeneration, biodegradable nonporous poly(l-lactic acid) (PLLA) films were prepared by using a solvent casting technique with...