Original paper
Impact of Oral Sildenafil on Exercise Performance in Children and Young Adults After the Fontan Operation
Abstract
Background— Children and young adults with single-ventricle physiology have abnormal exercise capacity after the Fontan operation. A medication capable of decreasing pulmonary vascular resistance should allow improved cardiac filling and improved exercise capacity. Methods and Results— This study was a double-blind, placebo-controlled, crossover trial conducted in children and young adults after Fontan. Subjects were randomized to receive...
Paper Details
Title
Impact of Oral Sildenafil on Exercise Performance in Children and Young Adults After the Fontan Operation
Published Date
Mar 22, 2011
Journal
Volume
123
Issue
11
Pages
1185 - 1193
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Notes
History